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Chemical Stomach Stapling
By sciencebase, Section News Posted on Mon Mar 03, 2008 at 02:51:46 AM PST
Two cell proteins that relax the gut and help accommodate a big meal have been identified by British scientists. The discovery could one day lead to a diet pill that works by preventing the stomach from expanding, almost like a chemical version of stomach stapling.

Writing in the Journal of Pharmacology and Experimental Therapeutics, Brian King and Andrea Townsend-Nicholson explored the molecular basis of relaxations of the gut. They found two protein receptors - P2Y1 and P2Y11 - involved in fast and slow relaxations of the gut. Modulating the activity of these receptors could become a target for drug designers hoping to control gut expansion. More...

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